What blood purification with hemoadsorption means for you
We specialize in a blood purification method called adsorption that can cleanse your blood of toxins and other unwanted substances that can cause disease. Here is how it works.
Keeping the balance to prevent damage in the body.
Our bodies are complex and function best when in balance.
Much of this control occurs in the blood, which transports thousands of substances that are required for life. The body regulates the amount of these substances, ensuring they remain within optimal levels, and makes adjustments as needed.
When our bodies are unable to regulate themselves, imbalance and disease is the result.
This can occur in cases of serious illness such as infections, or due to certain medicines or drugs. It can also happen if organs like our lungs, kidneys, or liver begin to fail. Typically, a combination of these reasons, and even others, result in life-threatening disease.
When this happens, it is important to address the imbalance as quickly as possible.
Blood purification is the one of the best ways to quickly restore balance by actively removing the harmful substances in our bloodstream, preventing damage, and helping us to recover or stay healthy.
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Our bodies are complex and function best when in balance.
Much of this control occurs in the blood, which transports thousands of substances that are required for life. The body regulates the amount of these substances, ensuring they remain within optimal levels, and makes adjustments as needed.
-
When our bodies are unable to regulate themselves, imbalance and disease is the result.
This can occur in cases of serious illness such as infections, or due to certain medicines or drugs. It can also happen if organs like our lungs, kidneys, or liver begin to fail. Typically, a combination of these reasons, and even others, result in life-threatening disease.
-
When this happens, it is important to address the imbalance as quickly as possible.
Blood purification is the one of the best ways to quickly restore balance by actively removing the harmful substances in our bloodstream, preventing damage, and helping us to recover or stay healthy.
That is where CytoSorbents comes in.
With our unique blood purification technology, we help cleanse the blood of harmful substances that other therapies and technologies cannot remove as efficiently. In doing so, our goal is to restore balance, protect the body, prevent or reduce serious complications, and help your doctor get you on the road to recovery faster.
Our blood purification technology
How tiny beads can make a vital difference
Our therapies are based on tiny porous polymer beads, each no larger than a grain of salt. They are compatible with blood and are non-toxic.
These beads have a special internal structure full of tiny holes and channels. When these beads are packed together in our CytoSorb® cartridge, they act like a sponge with a huge surface area—comparable to more than seven U.S. football fields or five soccer fields, in a single device. When blood is pumped through our cartridges, this large surface area is ideally suited to binding and removing a broad range of toxins and other harmful substances that traditional blood purification, like dialysis, cannot remove as efficiently.
Being broad-spectrum is one of the keys to the power of our technology, as so many dangerous substances can be out of balance in life-threatening diseases. But the technology is also selective by focusing on the removal of substances that are at very high concentrations, are a certain size, and can bind to the beads. Beneficial things such as cells, electrolytes, sugars, and antibodies go through the cartridge largely unaffected. Excessive levels of harmful substances like those that cause a “cytokine storm” and bacterial toxins, for example, go into the beads, are trapped and safely removed from the blood.
We are there the moment you need us
Should you or a loved one ever face health challenges in critical care, you can rest assured you will receive the care you need, because your doctor and healthcare team have access to complementary medical technologies and expert knowledge that improves the standard of care.
We are there every day, right beside your healthcare team. We provide them with the latest expertise and leading-edge technologies so that you get the best possible treatment, with the goal of the best possible outcome.
Additional Information
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- Waalders et al., Crit Care Med 2024; 52(4):e152-e153
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- Poli et al., Crit Care 2019; 23:108
- Gleason et al., Sem Thorac Cardiovasc Surg 2019; 31(4):783-793
- David et al., J Int Care 2017; 5:12
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CytoSorb can help your doctor stabilize your organ systems
Learn more about CytoSorb, our flagship adsorber, and how it can help with various types of potentially harmful substance imbalances
Voices around the world
Dr. Filipo Aucella
Italy, San GiovanniWhen we started to use CytoSorb®, we were very impressed by the rapid decrease of myoglobin concentrations, and the renal damage also improved very rapidly.
Dr. Maria Grazia Calabro
Italy, MilanCytoSorb is effective in reducing bilirubin, creatinine, and lactate in patients who are critically ill, mainly due to cardiogenic shock.
Dr. Tobias Hübner
Switzerland, MünsterlingenThe reason for us to use CytoSorb in the ICU was the lack of treatment options. We never had anything in sepsis, and CytoSorb® is the new star on the horizon.
Dr. Gabriella Bottari
Italy, RomeWe have applied CytoSorb in critical ill children with septic shock, with very good results.
Dr. Mihai Popescu
Romania, BucharestOur results show a potential benefit of CytoSorb in rebalancing liver function in patients with liver failure compared to MARS.
Dr. Serdar Gunaydin
Turkey, AnkaraOne of the most important indications for us to use CytoSorb® in is cardiac surgery, as it has also been cited in many guidelines.
Dr. Willem Pieter Brouwer
The Netherlands, RotterdamIntervention with CytoSorb may be associated with decreased all-cause mortality at 28 days compared to continuous renal replacement therapy alone.
Prof. Jean Louis Vincent
Belgium, BrusselsI would like to send my congratulations on the 10th anniversary of CytoSorb®. It is great how you have created a new way of blood purification therapy.
Juan Carlos Ruiz-Rodriguez
Spain, BarcelonaThis case highlights that cytokine hemoadsorption can lead to a rapid decrease in IL-10 levels, and significant hemodynamic improvement was achieved.
Dr. Gabriella Bottari
Italy, RomeHemoperfusion with CytoSorb in combination with continuous kidney renal therapy is a valuable therapeutic option in sepsis-associated acute kidney injury.
Dr. Askhat Saparov
Kazakhstan, AstanaCytoSorb was safe and well-tolerated in a pediatric patient and has proven its value as an adjuvant therapy for sepsis in pediatric patient populations.
Prof. Peter Pickkers
The Netherlands, NijmeganThe treatment with the CytoSorb® adsorber does reduce circulating concentrations at day one.
Dr. Abdulrahman Alharthy
Saudi Arabia, RiyadhIn this retrospective case series, CRRT with CytoSorb provided a safe rescue therapy in COVID-19 with associated AKI, ARDS, sepsis, and hyperinflammation.
Dr. Kai Singbartl
USA, PhoenixThe case represents the first successful application of CytoSorb in severe refractory neurotoxicity following treatment with chimeric-antigen-receptor T cells.
Dr. Henriette Roed-Undlien
Norway, OsloIn this in vitro study, apixaban levels were effectively reduced, and the clotting time and thrombin generation assays were normalized by the use of CytoSorb.
Dr. Aleksandr Burov
Russia, MoskowThis case series demonstrates that combined blood purification therapy including CytoSorb may have a role for septic shock patients with primary brain injury.
Prof. JW Awori Hayanga
USA, MorgantownIn COVID-19 ARDS on VV-ECMO + hemoadsorption, 90-day survival 74% and early intervention associated with shorter organ support, supporting “enhanced lung rest”.
Dr. Haider Ghaidan
Sweden, LundCytoSorb restored lung function and reduced PGD in lung transplantation. We suggest this treatment will increase tolerability of donor lungs in recipients.
Dr. Pawel Piwowarczyk
Poland, LublinCytoSorb Therapy was able to facilitate long-term regain of balance between inflammatory process, cytokine production, and bilirubin turnover in the liver.
Dr. Anna Krakowiak
Poland, LodzIn the event of poisoning with inorganic mercury compounds, CRRT using CytoSorb as an extracorporeal blood purification method may be considered.
Dr. Vanja Persic
Slovenia, LjubljanaUse of CytoSorb in shocked SIRS patients was associated with rapid IL-6 decrease and hemodynamic improvement, with improved observed vs predicted survival.
Dr. Simao Rodeia
Portugal, LisbonCytokine adsorption therapy with CytoSorb was employed with no direct complications, and helped control the inflammatory state.
Dr. Christopher Rugg
Austria, InnsbruckCatecholamines decreased within 24 h after initiation of CytoSorb Therapy; in-hospital mortality was significantly lower in the CytoSorb group (35.7% vs 61.9%).
Perfusionist Anna Holmen
Sweden, GothenburgThe accumulated norepi dose in the CytoSorb gp was half or less at all postop time points compared to controls..with significantly lower need for RBC.
Assoc. Prof. Berna Kaya Ugur
Turkey, GaziantepUse of CytoSorb achieved significant decreases in endocan, copeptin, IL-6, procalcitonin and C-reactive protein levels.
Dr. John Ferdinand
UK, CambridgeOur data suggest that adsorption of pro-inflammatory mediators from perfusate with CytoSorb represents potential intervention which may improve organ viability.
Prof. Dana Tomescu
Romania, BucharestThe use of CytoSorb in patients with severe acute pancreatitis was associated with improved hemodynamics and decreased inflammatory markers.
Dr. Arosha Minori Gunasekera
Sri Lanka, ColomboThis patient with acute liver failure was managed successfully with supportive therapy, aided by CytoSorb hemoadsorption and therapeutic plasma exchange.
Dr. Endre Nemeth
Hungary, BudapestIntraoperative hemoadsorption associated with better hemodynamics, lower post-op AKI and RRT, stable bilirubin, and shorter mechanical ventilation time and ICU
Dr. Fatime Hawchar
Hungary, SzegedThe first trial to investigate the effects of early extracorporeal cytokine adsorption treatment in septic shock applied without renal replacement therapy.
Dr. Wun Fung Hui
Hong Kong, Hong KongHemoadsorption with CytoSorb can be considered as an adjunctive therapy for children with severe rhabdomyolysis-associated acute kidney injury.
Dr. Maroua Eid
France, AngersThis case describes the successful use of CytoSorb with CRRT and extracorporeal life support in a combined way to overcome a critical phase of septic shock.
Dr. Marine Peyneau
France, ParisCytoSorb appears to be safe and promising to fight post-lung transplantation inflammation, and should be re-evaluated in a larger study.
Dr. Daniel Lovric
Croatia, ZagrebThis is the first study showing an increase in urinary output and a trend towards better survival among patients on VA ECMO treated with CytoSorb.
Prof. Pedja Kovacevic
Bosnia and Herzegovina, Banja LukaThis case series describes potential positive effects of hemoadsorption in preventing the development of systemic hyperinflammation after vvECMO in ARDS.
Certified Clinical Perfusionist Martin Clerici
Argentina, Buenos AiresIntraoperative use of CytoSorb® in an endocarditis patient with extensive cardiovascular history was associated with improvements in the hemodynamic situation.
Prof. Dorel Sandec
Romania, TimisoaraWe treated more than 75 patients with CytoSorb® because we realized, we feel, we see, we measure a significant effect on the evolution of the patient.
Dr. Voyka Gorjup
Slovenia, LjubljanaThe most prominent clinical effect is the lowering of vasopressors, hemodynamic stability, lowering of interleukins and in those patients who are on vvECMO…
Dr. Candido Amador
Panama, Panama CityIn my experience the vasopressor doses decreased, biomarkers of sepsis (…) and the inflammatory response as well as multiple organ function improved.
Assoc. Prof. Monir Sadat Hakemi
Iran, TehranIt seems that applying the CytoSorb in combination with CRRT in ICU septic patients with AKI is correlated with a significant decrease in mortality.
Dr. Yatin Mehta
India, GurgaonCytoSorb is indicated for use in conditions where elevated levels of cytokine and/or bilirubin and/or myoglobin exist.
Dr. L. Christian Napp
Germany, HannoverIn the most critically ill patients on ECMO support, we observed a drop in catecholamine demand and an improvement in clinical state on ECMO.
Prof. Steffen Mitzner
Germany, RostockWhat strikes you first is that you can stabilize patients in septic shock.