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Overview

The Therapeutic Aspects of CytoSorb Therapy

Supporting healthcare professionals in maintaining physiological balance.

CytoSorb® Therapy provides a hemoadsorption option designed to support the reduction of selected inflammatory mediators, helping to maintain physiological stability in critically ill patients. The therapy is intended to remove or reduce excessive levels of inflammatory mediators and other circulating molecules that, at elevated levels, may be harmful to the body. Published clinical experience has reported associations with parameters such as hemodynamic stability, tissue perfusion, and organ function when CytoSorb® Therapy is applied as part of a multimodal critical-care approach.

The CytoSorb® adsorber is an extracorporeal blood purification technology designed to reduce selected substances from blood or plasma that, at excessive levels, may be harmful to the body. It can be used in various clinical settings where hemoadsorption may support the management of inflammatory or substance-related imbalances as part of a multimodal treatment strategy.

  • CytoSorb® Therapy provides a hemoadsorption option designed to support the reduction of selected inflammatory mediators, helping to maintain physiological stability in critically ill patients. The therapy is intended to remove or reduce excessive levels of inflammatory mediators and other circulating molecules that, at elevated levels, may be harmful to the body. Published clinical experience has reported associations with parameters such as hemodynamic stability, tissue perfusion, and organ function when CytoSorb® Therapy is applied as part of a multimodal critical-care approach.

  • The CytoSorb® adsorber is an extracorporeal blood purification technology designed to reduce selected substances from blood or plasma that, at excessive levels, may be harmful to the body. It can be used in various clinical settings where hemoadsorption may support the management of inflammatory or substance-related imbalances as part of a multimodal treatment strategy.

Here, you can find more information on CytoSorb® Therapy and its application across different medical specialties. This section includes details on patient selection, timing, and dosing, as well as access to current published clinical research.

Use of CytoSorb in therapeutic areas

  • Critical Care
  • Cardiovascular Care
  • Liver Care
  • Kidney Care
  • Critical Care

    Intended to adsorb selected cytokines, inflammatory mediators, and toxins from whole blood to support management of systemic inflammatory responses.

  • Cardiovascular Care

    May be used in patients at risk of hyperinflammatory responses or intra-operatively during CPB to adsorb certain antithrombotic agents such as ticagrelor or rivaroxaban.

  • Liver Care

    Intended to remove selected cytokines, bilirubin, and other hydrophobic metabolites to support management of hyperbilirubinemia and systemic inflammation.

  • Kidney Care

    Intended to adsorb selected cytokines and myoglobin, either as a stand-alone modality or combined with renal-replacement therapies as part of a multimodal approach.

Proven safety

Over 250,000 hemoadsorption treatments over the last ten years.

Most peer-reviewed adsorber

Over 1,100 publications, abstracts, posters, manuscripts, and other resources.

Improved patient outcomes

With demonstrated efficacy across cardiovascular, hepatic, kidney, and critical care.

Simple system integration

Starting patient treatment with CytoSorb technology is fast and easy, with less work for nurses, and greater peace of mind.

Proprietary bead technology

Each CytoSorb cartridge features ISO 10993-certified porous polymer beads, for biocompatibility and hemocompatibility.

Concentration-dependent and size-dependent removal

Effective removal of cytokines, bilirubin, myoglobin, rivaroxaban, and ticagrelor—and minimal removal of important substances such as albumin.

CytoSorbents

Voices around the world

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Cardiovascular
Prof. Dr. Markus Krane
Munich, Germany

Post-operative bleeding and related post-operative blood transfusion, that are usually necessary, are reduced. And that’s a better outcome for the patient.

Cardiovascular
Dr. L. Christian Napp
Hannover, Germany

In the most critically ill patients on ECMO support, we observed a drop in catecholamine demand and an improvement in clinical state on ECMO.

Critical Care
Prof. Peter Pickkers
Nijmegan, The Netherlands

The treatment with the CytoSorb® adsorber does reduce circulating concentrations at day one.

Access Healthcare Professionals Area

This area is for Health Care Professionals only and provides reports about clinical experiences gained during the use of CytoSorbents products. The information presented reflects the opinions and procedural techniques of individual physicians and is not intended as medical advice. Physician experience, risks, patient outcomes and results may vary. This content is intended for Health Care Professionals outside the United States and Canada as CytoSorb has not yet been approved or cleared in the United States or Canada for any indication, except under an Emergency Use Authorization (EUA) by the US FDA.