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The Promise of Universal Plasma

HemoDefend-BGA is a development-stage filter designed to create “universal plasma” – plasma that does not need blood-typing and can be given off-the-shelf to anyone in need regardless of blood type – by removing anti-A and anti-B antibodies that make plasma blood-type specific.
*HemoDefend-BGA is a pre-clinical product under development that is not yet approved.

Many applications of life-saving plasma include trauma resuscitation, treatment of critically ill patients, and component purification, e.g.:

Clotting factors
Albumin
Intravenous immunoglobulin

In the U.S. alone, more than 10,000 units of fresh frozen plasma are administered daily, or 3.6 million units per year.

Replace standard plasma

 

With more than $16 million in funding from the U.S. Department of Defense, CytoSorbents has successfully developed and demonstrated a prototype HemoDefend-BGA adsorber that removes anti-A and anti-B antibodies from human plasma, with the goal of advancing our technology to human clinical trials and producing a one-size-fits-all low-titer “universal plasma” product that could replace standard plasma.

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CytoSorbents

Voices around the world

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Critical Care
Dr. Euclides Cruz
Pereira, Colombia

I remember a 23-year old man, who ingested a toxic substance: paraquat. No antidote, mortality is approx. 90%. CytoSorb worked really well, he survived.

Cardiovascular
Prof. Dr. Markus Krane
Munich, Germany

Post-operative bleeding and related post-operative blood transfusion, that are usually necessary, are reduced. And that’s a better outcome for the patient.

Critical Care
Dr. Yatin Mehta
Gurgaon, India

CytoSorb is indicated for use in conditions where elevated levels of cytokine and/or bilirubin and/or myoglobin exist.