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The Promise of Universal Plasma

HemoDefend-BGA is a development-stage filter designed to create “universal plasma” – plasma that does not need blood-typing and can be given off-the-shelf to anyone in need regardless of blood type – by removing anti-A and anti-B antibodies that make plasma blood-type specific.
*HemoDefend-BGA is a pre-clinical product under development that is not yet approved.

Many applications of life-saving plasma include trauma resuscitation, treatment of critically ill patients, and component purification, e.g.:

Clotting factors
Albumin
Intravenous immunoglobulin

In the U.S. alone, more than 10,000 units of fresh frozen plasma are administered daily, or 3.6 million units per year.

Replace standard plasma

 

With more than $16 million in funding from the U.S. Department of Defense, CytoSorbents has successfully developed and demonstrated a prototype HemoDefend-BGA adsorber that removes anti-A and anti-B antibodies from human plasma, with the goal of advancing our technology to human clinical trials and producing a one-size-fits-all low-titer “universal plasma” product that could replace standard plasma.

For partnership inquiries please contact us

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CytoSorbents

Voices around the world

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Critical Care
Prof. Olfa Hamzaoui
Reims, France

Prof. Hamzaoui shares a compelling summary of key highlights, clinical insights, and the growing role of CytoSorb Therapy in critical care.

Critical Care Liver
Dr. Marianna di Feliciantonio
Milan, Italy

We improved his state and we helped this patient to the transplantation, and we used the CytoSorb like a bridge for transplant.

Critical Care
Dr. David Castillo Bustamante
San Salvador, El Salvador

We used CytoSorb in three cases of severe dengue: we monitored the inflammatory response throughout the course of the therapy. We have had very good result.